The study of shock was greatly accelerated by the exigencies of the Great War. Master minds of various nations were concentrated on its problems. Numerous answers have been ventured; none of them have afforded complete satisfaction to the various inquirers. It would certainly be rash, if not actually hazardous, to attempt at this time any final solution in these columns. With the multiplication of theories, such a venture becomes increasingly more appalling if not discouraging. Probably a considerable number of somewhat unrelated states are concerned, so that multiple causes need to be dealt with rather than a uniform or individual etiologic situation. The warrant for renewed reference to the subject, however, lies in its intrinsic importance in medical practice; for shock is a hazard of everyday accidents as well as the misfortunes of the battlefield.
It is interesting to review some of the hypotheses that have been formulated to account
SHOCK. JAMA. 1930;95(3):204–205. doi:10.1001/jama.1930.02720030034013