In a previous paper,1 I offered a clinical study of the stool as evidence that summer diarrhea is more than the direct effect of heat on the organism. The conclusion was that most cases of summer diarrhea are characterized by an enormous discharge of cells in the stools which can rationally be explained only by an inflammatory reaction due to a local infection. The examination of the fresh diarrheal stool for cells has been a routine in my office for several years, and more than a thousand such examinations have been made.
My first efforts were directed almost entirely to a comparison of the number of cells and the clinical symptoms. In general, a liquid stool that showed more than ten cells to the field (diluted two-thirds with water), under the ordinary low power of a microscope, was regarded as strong evidence of a local infectious process. If, as
ZAHORSKY J. THE CYTOLOGY OF THE DIARRHEAL STOOL. JAMA. 1926;86(2):112–113. doi:10.1001/jama.1926.02670280032010