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News From the Centers for Disease Control and Prevention
July 14, 2015

Aggressive Public Health Response Prevented Meningitis Cases, Deaths

JAMA. 2015;314(2):116. doi:10.1001/jama.2015.7236

The massive public health response mounted in September 2012 to combat the largest US outbreak of fungal meningitis prevented substantial morbidity and mortality, investigators recently reported.

Contaminated injections of preservative-free methylprednisolone acetate (MPA) produced at a single compounding pharmacy in Framingham, Massachusetts, caused the outbreak. Three lots of MPA containing an environmental mold, Exserohilum rostratum, had been shipped to 75 injection facilities in 23 states, potentially exposing 13 534 people to the pathogen.

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