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March 20, 1926


JAMA. 1926;86(12):892. doi:10.1001/jama.1926.02670380082037

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To the Editor:  —In The Journal, January 2, page 31, Dr. Sigurd W. Johnsen reports a case of pituitary disease in a boy, aged 4. This is apparently not a case of pituitary disease, but a classical example of "pubertas praecox," a condition associated most commonly with pinealomas, as discussed in a recent paper by Horrax and Bailey (Arch. Neurol. & Psychiat. 13:423 [April] 1925). The literature on the pituitary body is already overburdened with a mass of conflicting opinions and theories of clinicians, experimental physiologists and pathologists. In the case referred to the only evidence of pituitary disease is a roentgenogram of an enlarged sella. This may be produced by a cerebral tumor or internal hydrocephalus, as well as a pituitary neoplasm. [The letter of Dr. Fink was referred to Dr. Johnsen, who replies:]

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