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Nicloux has long been recognized as the leading French authority and investigator in the field covered in this book. In it he has collected, digested and summarized not only his own life work but also the contributions of investigators in other countries. In general, Nicloux's observations and conclusions are in accord with those of Haldane in England, and of Henderson and Haggard in this country. Thus, he finds that carbon monoxide forms a compound with hemoglobin which may be dissociated under the action of oxygen, so that the oxygen carrying power of the blood is restored. He reports with approval the treatment of asphyxia by means of inhalation of oxygen plus carbon dioxide for the sake of the stimulant action of carbon dioxide on respiration. He still regards oxygen alone as of more value than air plus carbon dioxide for the treatment of asphyxia, in which he differs from Haldane,
L'oxyde de carbone et l'intoxication oxycarbonique. Etude chimico-biologique.. JAMA. 1926;86(12):897. doi:10.1001/jama.1926.02670380087051