As the use of the ketogenic diet in the treatment of epilepsy was started at the Mayo Clinic, it seems well to report at this time on the original series of cases of children who have been observed during the last eight years. Since the introduction of the diet as outlined by Wilder1 in 1921, the results of the treatment of idiopathic epilepsy in children have maintained the same proportion of cure and improvement to failure. Until April 1, 1930, we had prescribed the ketogenic diet for 272 children. Included in this number were twenty-nine cases of symptomatic epilepsy, and although two of the patients continue to be free from attacks, the results are not figured in the results in cases in which the patients have been observed for more than a year.
In 1927, our cases were classified2 so as to show every possible variation in type
HELMHOLZ HF, KEITH HM. EIGHT YEARS' EXPERIENCE WITH THE KETOGENIC DIET IN THE TREATMENT OF EPILEPSY. JAMA. 1930;95(10):707-709. doi:10.1001/jama.1930.02720100005002