The intravenous administration of glucose in the treatment of the vomiting of pregnancy was advocated in 1920 by Titus, Hoffman and Givens,1 who reported the results they obtained in the management of seventy-six cases, the chief factor in the treatment being the free exhibition of carbohydrates. These patients were divided into three groups; thefirst comprised the cases that could be classed as mild; the second included the moderately severe types, and the third was made up of those patients who were seriously ill.
In the first group were placed thirty-two of these patients. They were treated by rest in bed and free carbohydrate feeding. Small amounts of nourishment were given at frequent intervals, as it was found that the patients could retain seven small meals a day better than three rather bountiful ones. Some of the women also took 1 or 2 ounces (30 or 60 cc. ) of a
KING EL. GLUCOSE AND INSULIN IN THE TREATMENT OF THE VOMITING OF PREGNANCY. JAMA. 1926;86(19):1417-1420. doi:10.1001/jama.1926.02670450009003