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Comment & Response
July 28, 2015

Potential Adverse Effects of Anesthesia in Children

Author Affiliations
  • 1Department of Anesthesiology and Critical Care, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
  • 2Department of Anesthesiology, University of Wisconsin School of Medicine and Public Health, Madison
  • 3Department of Anesthesiology and Critical Care, Perelman School of Medicine at the University of Pennsylvania, Philadelphia
JAMA. 2015;314(4):408-409. doi:10.1001/jama.2015.7378

To the Editor In their Viewpoint, Dr Psaty and colleagues1 underscored the potential adverse effects of widely used anesthetics on the developing brain. The authors concluded: “No similar safety concerns have been raised for anesthetic agents in adults.” To the contrary, not only has this issue been raised, but it rests on a substantial body of preclinical and clinical research acquired over many decades.

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