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The prompt assuaging of pain caused by urologic complications of gonorrheal or nongonorrheal origin is an active problem. It most frequently presents itself in acute epididymitis, prostatitis and gonorrheal arthritis. While it is true that in the majority of instances the current therapeutic efforts, such as epididymotomy, protein therapy, diathermy, aspiration and immobilization of the affected joint, will succeed in furnishing eventual relief, there still persists a more or less extended period of severe pain until the final therapeutic effect materializes. Injections of procaine hydrochloride round the afflicted areas furnish prompt cessation of pain, which relief is of a satisfactory duration.
Areas of reflected pain (Head's zones) remote from the inflammatory focus may also be the seat of severe annoyance and will also become silent by the administration of this local anesthetic. It is known that renal and ureteral colics and perinephric pains are promptly relieved by paravertebral injections of
Kolischer G, Jones AE. THERAPEUTIC INJECTIONS OF PROCAINE HYDROCHLORIDE IN UROLOGIC COMPLICATIONS. JAMA. 1933;100(3):185–186. doi:10.1001/jama.1933.27420030002011a