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September 27, 1930


JAMA. 1930;95(13):936-937. doi:10.1001/jama.1930.02720130032012

Whenever the intake of fluid is for any reason restricted so that this, plus the water that may become available through metabolic processes, is less than the amount lost through the various channels of elimination, the conditions favorable to the production of anhydremia are created. Prolonged thirst has long been recognized as a menace to life. Often there are uncompensated and unsuspected losses of water, through the alimentary tract as well as the more familiar excretory paths of the lungs, kidneys and sweat glands, which produce a shortage in the water store of the organism. As Marriott1 has pointed out, severe anhydremia occurs when there is voluntary refusal of water for prolonged periods, for instance in the case of persons mentally deranged. It occurs in individuals exposed to the heat of the desert and in those working in such locations as deep mines and boiler rooms. Vomiting brought about

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