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The first two chapters deal with the anatomy and physiology of the breast. Most important, for the cancer question, is knowledge of the lymphatic drainage. Invasion of the axillary glands is an early and frequent event, while other glands are involved later. The early signs of cancer of the breast are enumerated. This knowledge is indispensable for every practitioner and will enable him to make early diagnosis. The later signs mean that not much chance for a cure is left. The seventh chapter gives the description of different varieties of breast cancer from the point of view of the pathologist. Concerning etiology, the author believes in chemical irritation as a factor in the cause of cancer of the breast. Of most actual interest is chapter XI, on roentgen therapy. White shows how difficult it is to judge the value of x-rays because of the difference of application as well as
Cancer of the Breast.. JAMA. 1930;95(13):958. doi:10.1001/jama.1930.02720130054038