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The author reviews the extensive literature on the relationship that exists between tuberculosis and the female generative organs. He discusses in detail experimental work on guineapigs to determine the effects of intracardial infection with tubercle bacilli. He also takes up the question of extragenital tuberculosis as a cause of disease in the female genitalia and, the reverse of this, the effect of the cyclic changes in the reproductive organs on extragenital tuberculosis. He further analyzes the effect of pregnancy and the puerperium on the course of extragenital tuberculosis. The author himself has done a considerable amount of experimental work on this subject and he used nongravid, gravid and puerperal guinea-pigs for his experiments. He found that intracardial injections of tubercle bacilli produced no effect on nonpregnant uteri; but during pregnancy and the puerperium many uterine infections were observed after the injections. In the large majority of pregnant animals, abortion, premature
Die Wechselbeziehungen zwischen der Tuberkuloseerkrankung und den Generationsvorgängen im weiblichen Organismus.. JAMA. 1930;95(13):959. doi:10.1001/jama.1930.02720130055042