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October 4, 1930


JAMA. 1930;95(14):1034-1035. doi:10.1001/jama.1930.02720140056024

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Progress of the Lübeck Investigation  Following the declaration of July 8, the federal ministry of the interior, under date of September 10, has published the following statement with regard to the progress that is being made in the investigation of the causes and conditions that led to the death from tuberculosis of more than sixty infants, in Lübeck, who had been inoculated with the B C G vaccine against tuberculosis:The scientific investigations that have been carried on in the bureau of the federal health service, by Prof. Dr. Ludwig Lange, have produced these results:

  1. The epidemiologic course of the cases of morbidity and the fatal cases shows marked periodic fluctuations, which bring out the fact that the vaccine materials that were prepared and administered at different times had a varying pathologic action. In contrast with certain periods with comparatively high morbidity and high mortality, there are others with a

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