October 11, 1930


JAMA. 1930;95(15):1110-1111. doi:10.1001/jama.1930.02720150050019

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The Evolution of Spirochetes  Before the Société de biologie, Levaditi and Li Yuang Po recently presented a communication on the evolutional cycle of Spirochaeta pallida, Spirochaeta pertenuis and Spirochaeta cuniculi. These spirochetes have a cycle in which one of the phases is represented by parasites arranged in more or less compact chains and circular masses. This stage precedes that of the transformation into nearly ultramicroscopic granules. Various phases of this evolutional cycle may be found in the lesions of the skin and the mucosa, and in the brain of patients with dementia paralytica. Such brains, stained by the Dieterle method (silver impregnation), show in places spirochetes in the evolutional stage, in chains and compact masses, and also the process of transformation into ultramicroscopic granules.

The Bandage Sign  P. Emile Weil has brought up again a study of the signe du lacet, or the bandage sign, which consists in the appearance,

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