Mycotic hand eruptions frequently accompany similar ones on the feet. To explain this, Williams1 and Bloch2 independently advanced the hypothesis that the lesions on the hands, which are usually free of fungi, are dermatophytids secondary to foci on the feet which contain the organisms. Walthard3 reported a case from Bloch's clinic, substantiating this view. In this patient fungi were present in lesions on the feet, and after a positive trichophytin test, a focal reaction took place in the hand lesions. Werner Jadassohn and Peck,4 analyzing twenty-four cases, were able to support the belief that such concomitance existed between the foot and hand manifestations, the latter being trichophytids.
Subsequently Peck5 was able to provoke the complete syndrome experimentally. In another patient with a demonstrated fungus infection of the feet and dyshidrotic vesicular lesions on the hands, he obtained a positive blood culture for fungi identical with
HIGHMAN WJ. EPIDERMOPHYTOSIS AND EPIDERMOPHYTIDS OF THE HANDS. JAMA. 1930;95(16):1158-1160. doi:10.1001/jama.1930.02720160018005