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This is an interesting and valuable study of iodized oils used by neurologists. The authors first discuss the anatomy of the subarachnoid space in brief and show that it is divided into an anterior and a posterior compartment, so that in clinically tilting a patient to observe block or partial arrest of iodized oil one must do it with the patient both on his back and on his abdomen. They have experimented with various types of iodized oils in varying amounts and found that some of the oils are rather irritating, especially when given in large amounts. They have found not only that the usual oils are irritating but also that the technic of preparation is such that considerable acetic acid and chloroform is often still present in the oil, which causes marked irritation of the leptomeninx. They have devised a new method of preparation of the emulsion for which
Iodized Oils as an Aid to the Diagnosis of Lesions of the Spinal Cord and a Contribution to the Knowledge of Adhesive Circumscribed Meningitis.. JAMA. 1930;95(16):1199. doi:10.1001/jama.1930.02720160059033