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This work considers not only the erythremia of altitude but also the other physiologic responses. It discusses changes in basal metabolism, the shift in the acid-base equilibrium and the altered constituents of the urine. Studies of the oxygen saturation of the blood, of the elimination of the carbon dioxide and of the change in the carbon dioxide tension are included. The studies were made at various altitudes between 150 and 4,500 meters. While nothing particularly new is offered in this field, the subject has been thoroughly investigated and the results are set forth in detail. The various theories of acclimatization are discussed as well as the relationship between the erythremia of altitude and that of other causes. A fairly comprehensive bibliography is attached. A little more care might have been used in the proof reading, particularly in reference to proper names. It rather annoys the American reviewer to see Osler
Les érythrémies de l'altitude: Leurs rapports avec la maladie de Vaquez.. JAMA. 1930;95(16):1200. doi:10.1001/jama.1930.02720160060038