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April 22, 1933

Die Schwangerschaftsdiagnose aus dem Harne: Praktische und wissenschaftliche Ergebnisse.

JAMA. 1933;100(16):1283. doi:10.1001/jama.1933.02740160067047

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This monograph was published on the fifth anniversary of the author's discovery of the presence of large amounts of hormone in the urine of pregnant women, a discovery that led to the Aschheim-Zondek biologic test for early pregnancy. In the present book, the author discusses the various biologic methods for detecting pregnancy, the original technic of Aschheim and Zondek, and the various modifications of it. He also takes up the many practical applications of the test in conditions other than normal pregnancy, such as intra-uterine death of the ovum, extra-uterine gestation, hydatidiform mole, chorionepithelioma and illnesses in nonpregnant individuals. The sources of error and the forensic significance of the test are also discussed. From the literature Aschheim collected reports of 8,086 cases in which his test was used and it proved to be reliable in 98 per cent. He also collected reports of 1,358 cases in which rabbits were used

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