[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.211.207.116. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
September 11, 1926

SKIN TESTS IN MEASLES

Author Affiliations

CHICAGO
From the John McCormick Institute for Infectious Diseases.

JAMA. 1926;87(11):846. doi:10.1001/jama.1926.02680110046013
Abstract

In skin tests with killed cultures of the green-producing diplococcus from measles, Tunnicliff1 obtained positive reactions in 100 per cent of persons who had not had measles, and in only 4 per cent of those with a history of measles. This intracellular toxin was neutralized in persons with a negative history of measles by convalescent human measles serum, but not by the serum of a person who had not had measles. The toxin was neutralized in rabbits by convalescent human measles serum and by the serum of goats convalescing from the reaction produced by measles diplococci, but not by normal goat serum. The measles toxin produced reactions in normal rabbits, but not in rabbits immunized against measles. Berkefeld W filtrates of cultures of measles diplococci failed to produce any reactions.

Recently, Ferry and Fisher2 have demonstrated an extracellular toxin in filtered cultures of green-producing streptococci from measles with

First Page Preview View Large
First page PDF preview
First page PDF preview
×