Is isotonic fluid associated with a lower incidence of hyponatremia when compared with hypotonic fluid for maintenance intravenous fluid therapy in children?
Compared with hypotonic fluid, isotonic fluid is associated with a lower incidence of hyponatremia, without evidence of an increase in adverse outcomes.
McNab S. Isotonic vs Hypotonic Intravenous Fluids for Hospitalized Children. JAMA. 2015;314(7):720-721. doi:10.1001/jama.2015.7918