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The authors review recent literature on the importance and incidence of typhoid and paratyphoid carriers, the method of identification of a carrier and the possible methods of treatment. They also include a study of their own on eight intestinal excreters and two urinary carriers. The practical significance of intermittence of excretion is fully recognized. Nonsurgical treatment of intestinal excreters is considered ineffective; but, when the gallbladder is the site of infection, the application of surgical measures, cholecystectomy or, more rarely, cholecystotomy has yielded highly satisfactory results. The report is clear, concise and marked by good judgment.
Chronic Enteric Carriers and Their Treatment.. JAMA. 1933;100(22):1803. doi:10.1001/jama.1933.02740220069051