The history of the development of this method as well as the chemical and pharmacologic properties of the substance employed are dealt with in greater detail in the paper by Dr. Swick presented before the Section on Urology.
Swick states that the present substance, prepared by Professors Binz and Räth, is nontoxic, very soluble in water, neutral in reaction and under normal conditions excreted as such through the urinary tract within eight to twelve hours to the extent of from 85 to 95 per cent. Iodism has never been observed. Its tolerance is exceedingly great. From about 45 to 65 per cent of the substance is normally excreted during the first two hours. For this reason, the urograms show their greatest intensity during this period.
The technic of administration is as follows: A 40 per cent solution is made up in doubly distilled water to a volume of 100 cc.,
JACHES L. INTRAVENOUS UROGRAPHY (SWICK METHOD). JAMA. 1930;95(19):1409-1412. doi:10.1001/jama.1930.02720190021005