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It is quite generally believed that it is not desirable to advise cholecystography in jaundiced patients; in the first place, because nonvisualization usually results, and, in the second place, because the reaction to the dye may be unduly severe.
In the course of the past eighteen months, ten jaundiced patients have been seen among a group of some hundreds coming in a routine manner for cholecystography. In all except one of these cases, the examination has yielded useful information without ill effects to the patients.
Tetraiodophenolphthalein sodium is excreted in the bile by the liver shortly after intravenous injection, and diverted into the gallbladder by the action of the sphincter of the common duct, if the subject is fasting. The filling of the gallbladder seems to depend almost entirely on the occlusion of the common duct. Once inside the gallbladder, the bile and dye become concentrated by the absorption of
Rudisill H. GALLBLADDER VISUALIZATION IN JAUNDICED PATIENTS. JAMA. 1930;95(19):1425. doi:10.1001/jama.1930.27210190002009b