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JAMA Clinical Evidence Synopsis
September 8, 2015

Rapid Diagnostic Testing for Plasmodium vivax and Nonfalciparum Malaria in Endemic Areas

Author Affiliations
  • 1Public Health, Epidemiology and Biostatistics, University of Birmingham, United Kingdom
  • 2Department of Clinical Sciences, Liverpool School of Tropical Medicine, United Kingdom

Copyright 2015 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA. 2015;314(10):1065-1066. doi:10.1001/jama.2015.6719

Clinical Question  How sensitive and specific are rapid diagnostic tests (RDTs) for diagnosing Plasmodium vivax and nonfalciparum malaria in endemic areas?

Bottom Line  Vivax-specific RDTs were highly sensitive and specific when compared with microscopy (the gold standard) for detecting P vivax malaria. RDTs that can only distinguish Plasmodium falciparum from nonfalciparum malaria were less sensitive.