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October 30, 1926

HODGKIN'S DISEASEWITH ESPECIAL REFERENCE TO ITS TREATMENT BY IRRADIATION

JAMA. 1926;87(18):1445-1452. doi:10.1001/jama.1926.02680180017005
Abstract

This paper is based on the study of 173 cases of Hodgkin's disease, treated at the Howard A. Kelly Hospital between October, 1913, and November, 1925.

My original intention to cover both Hodgkin's disease and lymphosarcoma was abandoned on account of the immensely greater material and the difficulty in analyzing it, and also from the fact that the two diseases are histologically and, in many ways, clinically quite distinct. The first is an infection, in all likelihood, and the second a neoplasm. I believe that a large number of cases which have been treated and which showed the general distribution in the glands, the fever and the other clinical signs of Hodgkin's disease, may have been Hodgkin's disease. The tissue examinations, however, showed only a lymphoid hyperplasia and, as a consequence, these cases have been classified as pseudoleukemia, or lymphosarcoma.

The term Hodgkin's disease, first employed by Samuel Wilks, 1

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