October 30, 1926


JAMA. 1926;87(18):1493. doi:10.1001/jama.1926.02680180065024

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The Action of Insulin on Diabetes in Childhood  At the meeting of Hungarian pediatricians, held recently, Dr. Francis Rohrbock of Budapest recounted his experiments with insulin in children. He treated eighteen patients for two years; twelve received insulin, while the rest were treated with diet only. Of the twelve patients treated with insulin, two were saved from coma; in another case, insulin had no beneficent action and the patient succumbed. In final analysis, the mortality rate of those treated with insulin was about 50 per cent. According to Dr. Rohrbock, it is impossible in general permanently to raise the carbohydrate tolerance of patients. He thinks that the increase in weight attained in some cases with insulin is only water retention, and is not constant, because on a salt-poor diet the increase in weight usually disappears. He warned his audience against putting insulin into the hands of children or of parents.

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