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November 15, 1930


JAMA. 1930;95(20):1507-1508. doi:10.1001/jama.1930.02720200043014

In a recent issue of The Journal,1 consideration was given to the failure of many persons, who undoubtedly consume food fuel in excess of their requirements, to deposit fat. According to Wilder2 of the University of Chicago, obesity may not be just a matter of excessive eating. Some abnormality, possibly an inadequacy of the mechanism of luxus consumption, must be present to account for the inability to rid the body effectively of excesses of food. In any event there are enough persons in whom the balance between intake and output is favorable to accumulation of reserves to make the question of the management of obesity conspicuous. It might be expected from a biologic point of view that the body should include a protective or regulatory mechanism that would help to avert wide fluctuations in its adult size or weight. The stimulation of metabolism for this purpose, as Wilder

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