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JAMA Clinical Evidence Synopsis
September 22/29, 2015

Oxycodone for Cancer Pain in Adult Patients

Author Affiliations
  • 1National Collaborating Centre for Cancer, Wales, United Kingdom
  • 2Leeds Institute of Health Sciences, University of Leeds, Leeds, United Kingdom
  • 3Welsh Institute for Health and Social Care, University of South Wales, United Kingdom

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JAMA. 2015;314(12):1282-1283. doi:10.1001/jama.2015.8556

Clinical Question  Is oxycodone associated with greater efficacy and fewer adverse events compared with alternative analgesics for cancer pain?

Bottom Line  Oxycodone was not associated with superior cancer pain relief or fewer adverse effects compared with other strong opioids, such as morphine or oxymorphone. However, the quality of the evidence was low.