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Epidemic Encephalitis: Report on the Sheffield Outbreak
The medical research council has published a report on "The Sheffield Outbreak of Epidemic Encephalitis in 1924." The disease has been intensively studied by a special committee, and the conclusions reached are of interest and importance. Professor Wynne, who has dealt with the epidemiology, urges that statistical estimates of the incidence and fatality be accepted with reservation owing to the occurrence of unrecognized, mild and abortive cases. The evidence already available as to increased susceptibility to infection in males and increased liability to death in females is confirmed by the Sheffield figures, as is also the idea that there is increased liability to infection in males between the ages of 15 and 30 years. Evidence has not been obtained that the disease is in any way connected with social conditions, such as over-crowding, poverty or insanitary conditions, nor has any connection been established
LONDON. JAMA. 1927;88(1):41-42. doi:10.1001/jama.1927.02680270041017