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The author states that his work is based on experimental physiologico-anatomic studies undertaken from 1899 to 1916, and on clinical work carried on from 1900 to 1923. The first three parts, experimental studies, were done at intervals of five years each, while the remaining parts of the book were completed without interruptions. This is his excuse for certain shortcomings, such as frequent repetitions and a slight unevenness in the sequence of several chapters. Because of its originality, the experimental portion, comprising 166 pages, or about one half of the book, needs especial mention. In this the author attempts, by experimental methods, to reproduce as nearly as possible the phenomena observed in human "genuine epilepsy." He measures and graphically describes a type of spasm which he calls "myoclonic," produced in animals by various irritants; then the animal is killed and its nervous tissues are examined. The author is of opinion that
Epilepsie: Vergleichende Pathogenese. Erscheinungen. Behandlung.. JAMA. 1927;88(2):122. doi:10.1001/jama.1927.02680280052032