In this paper I shall consider only the toxemias of pregnancy as they occur during the last third of pregnancy, and particularly the treatment of eclampsia. I use the plural rather than the singular for the reason that the term toxemia is employed very loosely, and is used by many to include a group of conditions that vary from a trace of albumin in the urine without clinical symptoms to actual eclampsia, or even to acute yellow atrophy of the liver. Indeed, many go so far as to claim that the several conditions merely represent stages in the evolution of a single disease process.
For years, I have contended that such a conception is erroneous and tends to complicate rather than to clarify the question, as I believe that several distinct entities have to be dealt with and that any attempt to gather them into a single group will retard
WILLIAMS JW. THE TOXEMIAS OF PREGNANCY, AND THE TREATMENT OF ECLAMPSIA. JAMA. 1927;88(7):449–454. doi:10.1001/jama.1927.02680330001001