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The author of this work is one of the best known English laryngologists who has contributed many excellent articles on rhinology and allied subjects. In this monograph much of the space is devoted to the subject of focal sepsis, or focal infections. Beginning with an historical survey of toxemia, bacteremia and selective affinities of organisms and toxins, the pathways of invasion, and the general symptoms and signs of focal sepsis, there is a discussion in considerable detail of complications involving the respiratory and intestinal tracts, the heart, the joints, the skin and the eyes. The author is more imbued with the firm belief that focal infection, or sepsis, as he terms it, is the cause of general conditions than is at present perhaps the tendency of physicians in America. Some years ago focal infections were used to explain the causation of almost every painful inflammatory condition in the body. The
Chronic Nasal Sinusitis and Its Relation to General Medicine: Based on the Author's Semon Lecture, University of London. The Toll of Nasal Focal Sepsis on Body and Mind.. JAMA. 1930;95(24):1857. doi:10.1001/jama.1930.02720240067032