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December 13, 1930

Experimentelle Bidrag til Spørgsmaalet om Hypophysens Livsvigtighed.

JAMA. 1930;95(24):1857. doi:10.1001/jama.1930.02720240067033

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This is a thesis submitted as part of the requirements for the degree of doctor of medicine from the University of Copenhagen. In addition to discussing the anatomy and physiology of the hypophyseal region, the author stresses particularly the vital significance, as determined by extirpation and destruction, of the part of the tuber or infundibulum that forms the floor of the third ventricle. Within a period varying from a few hours to a few days after the removal of this part there develops in the dog apathy, somnolence, coma and death. The mechanism of death under these circumstances requires further investigation. The results described in this thesis may have a bearing on the methods and results of operations for hypophyseal and brain tumors.

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