Resorcin sensitization is encountered from time to time in dermatologic practice. What the percentage of sensitized individuals may be is unknown at present. Urbach1 says that only one person in several thousand will be found sensitized, and Nathan and Stern2 state that cases of resorcin sensitization are rare.
Resorcin (metadihydroxybenzene) is an ingredient of many hair lotions sold in the shops and used by hair dressers and barbers. Examination of the prescription files of a pharmacy doing a large prescription business discloses that many prescriptions for resorcin are filled daily and that resorcin is prescribed about four times more frequently than is monoresorcinol acetate (introduced as Euresol).
An informal inquiry of some of the druggists doing a large volume of business in the Chicago loop district indicates that the sale of Anusol suppositories is heavy. No one interviewed, however, had had any complaint of irritation set up by
Mitchell JH. RESORCIN ANAL DERMATITIS DUE TO RESORCIN IN ANUSOL SUPPOSITORIES. JAMA. 1933;101(14):1067-1069. doi:10.1001/jama.1933.27430390002007b