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The Rôle of the Chlorides in Operative Shock
Mr. Robineau has contributed an analysis of the conception that assigns great importance, in accidents due to postoperative shock, to hypochloridemia. Prof. F. Legueu, B. Fey, Palozzoli and Mlle. Lebert have also presented a communication to the Academy of Medicine. According to Legueu, in seeking to comprehend the mechanism of this source of postoperative disturbance one is surprised to find that the chlorides diminish simultaneously in the blood and the urine. In general, there is not a loss but merely an abnormal distribution of chlorides. Numerous experiments on animals (wounds of the liver, kidneys or muscles) have shown that the chlorides become localized in the region of the operative wound, where one finds a constant local hyperchloriduria, which progresses for several days after the operation, the time period varying with the importance of the traumatism, while the degree of traumatism explains largely
PARIS. JAMA. 1933;101(14):1086-1087. doi:10.1001/jama.1933.02740390044018