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This is an important work. Possibly no one can speak with more authority on the subject of cancer of the larynx than Sir St. Clair Thomson, who has devoted many years to careful, painstaking scientific work. The history and the frequency of laryngeal carcinoma, its pathology, signs and symptoms as well as the diagnosis and prognosis are discussed. One of the most important points is that with reference to the mobility of the vocal cords. It was thought for many years that one of the earliest signs of cancer involving the cords was an impairment of mobility. It is shown by Thomson and others and emphasized by him that this is erroneous and he has demonstrated that often it is a rather late symptom; therefore, a reliance on its early appearance often leads to mistakes in diagnosis until the disease is far advanced. With reference to the actual differential diagnosis
Cancer of the Larynx.. JAMA. 1930;95(24):1859. doi:10.1001/jama.1930.02720240069039