This report is based on an analysis of the clinical features presented by sixty-one patients with primary carcinoma of the bronchus in whom the diagnosis was verified by histologic examination of tissue removed bronchoscopically (thirty-six cases), surgically (eight cases) or post mortem (twenty cases). In this group were fifty men and eleven women, a ratio of 4.5 men to 1 woman. The youngest patient was a woman, aged 24, and the oldest a man, aged 73. Only two patients were under 35 years of age (24 and 27). Twentyseven patients (44.2 per cent) were between 35 and 45. The predominance among men, the incidence after the age of 35, and especially in the decade between 35 and 45, are factors of significance in diagnosis.
The increasing clinical interest in the early diagnosis of primary carcinoma of the lung has been stimulated by the recognition that origin from the larger bronchi
FUNK EH. THE CLINICAL MANIFESTATIONS OF PRIMARY BRONCHIAL CARCINOMA. JAMA. 1930;95(25):1879-1882. doi:10.1001/jama.1930.02720250001001