To the Editor Dr Stéphan and colleagues1 demonstrated, in a large multicenter noninferiority randomized trial, that high-flow nasal oxygen could be as effective as noninvasive ventilation in preventing or treating postextubation acute hypoxemic respiratory failure after cardiothoracic surgery. High-flow nasal oxygen is an emerging oxygenation technique with numerous physiological and clinical advantages.2 However, some important issues should be addressed before drawing definitive conclusions from the study.
Girault C, Rabbat A. High-Flow Nasal Oxygen Therapy for Postextubation Acute Hypoxemic Respiratory Failure. JAMA. 2015;314(15):1644. doi:10.1001/jama.2015.11417