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Comment & Response
October 20, 2015

High-Flow Nasal Oxygen Therapy for Postextubation Acute Hypoxemic Respiratory Failure

Author Affiliations
  • 1Department of Medical Intensive Care, Charles Nicolle University Hospital, Rouen, France
  • 2Department of Pneumology and Respiratory Intensive Care, Cochin University Hospital, Paris, France
JAMA. 2015;314(15):1644. doi:10.1001/jama.2015.11417

To the Editor Dr Stéphan and colleagues1 demonstrated, in a large multicenter noninferiority randomized trial, that high-flow nasal oxygen could be as effective as noninvasive ventilation in preventing or treating postextubation acute hypoxemic respiratory failure after cardiothoracic surgery. High-flow nasal oxygen is an emerging oxygenation technique with numerous physiological and clinical advantages.2 However, some important issues should be addressed before drawing definitive conclusions from the study.

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