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Article
May 7, 1927

CAUSE OF GROWTH OF SARCOIDS OR OIL TUMORS

Author Affiliations

ST. LOUIS
From the Department of Surgery, Washington University School of Medicine, and the Research Laboratories of the Barnard Free Skin and Cancer Hospital.

JAMA. 1927;88(19):1460-1462. doi:10.1001/jama.1927.02680450004002
Abstract

It has now been well established that not only paraffin, liquid petrolatum 1 and coal tar 2 but also vegetable 3 and animal oils 4 become encapsulated when introduced into the tissues. It is also known that many of these oil tumors become active at a later time and cause pain, swelling and redness. Recently Zemansky 5 has seen a case in which quinine in olive oil had been introduced hypodermically into the fat of the buttocks during an attack of influenza, in Italy, in 1918. In 1926, one of the three tumors resulting from these injections enlarged rapidly in size and became red and painful. On examination in New York at that time, a fluctuating tumor was found and opened. It contained an oily material, but there was no definite pus. The wound refused to heal, and the lesions were excised. A typical but very cellular oil tumor was

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