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What medical therapies are associated with greatest efficacy and fewest adverse events for treating hirsutism?
Oral contraceptive pills (OCPs) have been associated with improvement for mild hirsutism, as has flutamide (250 mg) twice daily and spironolactone for more severe cases. Finasteride and gonadotropin-releasing analogues are associated with inconsistent results and metformin is not associated with benefit.
van Zuuren EJ, Fedorowicz Z. Interventions for Hirsutism. JAMA. 2015;314(17):1863-1864. doi:10.1001/jama.2015.11743