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Comment & Response
November 10, 2015

Thrombophilia and the Risk of Recurrent Venous Thromboembolism

Author Affiliations
  • 1Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania
JAMA. 2015;314(18):1975-1976. doi:10.1001/jama.2015.12598

To the Editor The Prolonged Anticoagulation During Eighteen Months vs Placebo After Initial Six-month Treatment for a First Episode of Idiopathic Pulmonary Embolism (PADIS-PE)1 trial investigated extended duration of warfarin therapy after a first episode of unprovoked pulmonary embolism. The results may be biased by the inclusion of patients with both identified and unidentified thrombophilias.

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