Over the last 2 decades, understanding of risk factors, prevention, and acute and long-term treatment of venous thromboembolism (VTE) have increased substantially. This disorder, comprising deep vein thrombosis (DVT) and pulmonary embolism, is the third leading vascular diagnosis after myocardial infarction and stroke, contributes to at least 3.2% of cardiovascular-related deaths in the United States (43 579 cases) and may affect 300 000 to 600 000 individuals annually.1 Surveillance for fatal and nonfatal VTE is not performed in the United States, so these statistics are imprecise.
Cushman M, Creager MA. Improving Awareness and Outcomes Related to Venous Thromboembolism. JAMA. 2015;314(18):1913-1914. doi:10.1001/jama.2015.15107