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February 1, 1941


JAMA. 1941;116(5):404. doi:10.1001/jama.1941.62820050003009a

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A physician aged 48 with a history of autumnal hay fever since age 3 and gastric intestinal sensitivity to most of the cabbage family and attacks of severe headaches, sometimes of the migraine type, after the eating of cabbage and other vegetables in the same group, suffered a severe dermatitis from the wearing of a watch bracelet of the new synthetic, flexible, glass-like substance sold under various trade names. The onset of the symptoms was delayed two months after the purchase of the watch bracelet, although it was worn daily on the left wrist. The first manifestation was itching and erythema, followed in about twelve hours with typical urticarial wheals. These were found around the entire wrist except in the area under the watch itself. Although the first symptoms, itching and erythema, affected the entire area of skin with which the watch bracelet was in contact, the eruption at the

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