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JAMA Diagnostic Test Interpretation
November 17, 2015

Evaluating an Elevated Screening PSA Test

Author Affiliations
  • 1Division of General Internal Medicine, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston
  • 2Department of Hematology—Oncology, Dana-Farber Cancer Institute at St Elizabeth’s Medical Center, Brighton, Massachusetts
JAMA. 2015;314(19):2073-2074. doi:10.1001/jama.2015.12614

A 59-year-old white man in good health, with no family history of prostate cancer, visited his primary care physician. His digital rectal examination (DRE) revealed an enlarged prostate without nodules. He previously made an informed decision to undergo prostate-specific antigen (PSA) screening for prostate cancer. His PSA history is displayed in the Table.

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