A 59-year-old white man in good health, with no family history of prostate cancer, visited his primary care physician. His digital rectal examination (DRE) revealed an enlarged prostate without nodules. He previously made an informed decision to undergo prostate-specific antigen (PSA) screening for prostate cancer. His PSA history is displayed in the Table.
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Barry MJ, Hayes JH. Evaluating an Elevated Screening PSA Test. JAMA. 2015;314(19):2073-2074. doi:10.1001/jama.2015.12614