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May 21, 1927


Author Affiliations

From the medical service of the Michael Reese Hospital.

JAMA. 1927;88(21):1626-1627. doi:10.1001/jama.1927.02680470012006

The simultaneous occurrence of diabetes mellitus and leukemia in the same person is quite unusual. In 1920, Fitz1 reported a case and summarized two others already described in the literature. The first case was described by Rebitzer, 2 and occurred in a man, aged 56, who had had diabetes for six years. Four months before death, which occurred in diabetic coma, the patient began to complain of a sense of pressure under the ribs and an abdominal swelling. On examination, a greatly enlarged spleen was felt and the leukocyte count was 555,000. At necropsy the observations were characteristic of leukemia, but it cannot be stated from the report whether the leukemia was of the myelogenous or the lymphatic type. Grossly and microscopically, nothing abnormal was noted in the pancreas.

The second case, reported by Schwarz, 3 occurred in a boy, aged 13 years. In this instance the onset of

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