[Skip to Content]
[Skip to Content Landing]
Article
March 15, 1941

EARLY DIAGNOSIS OF MALIGNANT METASTASES TO THE SPINEA CLINICAL SYNDROME

Author Affiliations

LOS ANGELES
From the Medical Clinic of the Cedars of Lebanon Hospital.; Drs. Wolfson and Reznick are clinic assistants at the Cedars of Lebanon Hospital; Dr. Gunther is adjunct physician to Cedars of Lebanon Hospital and assistant clinical professor of medicine, College of Medical Evangelists.

JAMA. 1941;116(11):1044-1048. doi:10.1001/jama.1941.02820110008003
Abstract

Adequate roentgen therapy of malignant metastatic lesions often produces such dramatic relief of pain and such remarkable regression of the lesions that the evaluation of early findings related to pain, erythrocyte sedimentation rate and serum phosphatase level is worthy of discussion and clarification.

Since roentgen ray therapy is the only hope for successful treatment, an early diagnosis becomes imperative. The feeling of many physicians concerning the possibilities of an early diagnosis and the successful treatment of demonstrable malignant metastases to the spine has been, unnecessarily, one of pessimism and futility. Our observations disclosed certain constant features attending metastatic lesions in the vertebrae. An accurate diagnosis can be made long before roentgen ray evidence is present. The constant features mentioned suggest a syndrome based on (1) the character of the pain, (2) the changes in the erythrocyte sedimentation rate and (3) the level of the serum phosphatase.

EVALUATION OF ROENTGEN RAY 

First Page Preview View Large
First page PDF preview
First page PDF preview
×