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Infertility has traditionally been defined as failure to achieve pregnancy after 12 months of regular unprotected intercourse with the same partner; because approximately half of these couples will conceive without intervention over the next 12 to 24 months, the term subfertility is also sometimes used.1 Self-reported infertility, using the 12-month definition, affected approximately 6% of married women aged 15 to 44 years in the 2006-2010 National Survey of Family Growth (the most recent available data).2 There are a number of etiologies for subfertility in both women and men,3,4 and treatments directed at specific causes, such as anovulation secondary to polycystic ovary syndrome, can be effective.5
Myers ER. Repeated In Vitro Fertilization Cycles for Infertility. JAMA. 2015;314(24):2627-2629. doi:10.1001/jama.2015.17297