Coffee is one of those dietary adjuncts which modern man has employed, like tea, alcohol, tobacco—and perhaps one ought to add the ubiquitous chewing gum—presumably to increase the pleasure of his existence quite independently of any need which they might serve in the organism. The demand for all of these products is created by an artificial rather than a natural appetite. Purveyors of the various articles of commerce have expended considerable effort and money to indicate on billboards and in other advertising spaces wherein the human mechanism is benefited and life made worth living by some particular brand of cigaret, whisky, tea, coffee, etc. There has at length arisen an amusing competition in which alcohol-free beverages, detannated or decaffeinated coffee, and even nicotin-free tobacco are extolled for the supposed advantages without the alleged defects of the respective products concerned.
Coffee and Protein Metabolism. JAMA. 2016;315(1):92. doi:10.1001/jama.2015.17069