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February 17, 1934


JAMA. 1934;102(7):540. doi:10.1001/jama.1934.02750070038013

In the Science of Nutrition, Graham Lusk stated that the source of mechanical work must be the metabolism, for mechanical energy cannot be derived from nothing. The necessary energy might be obtained in one of two ways: either at the expense of a proportionate reduction in the quantity of heat liberated by the resting organism or by an increase in the amount of the metabolism. In the former case, work would diminish the heat production and might cool the tissues, which is not observed to take place. If work were done at the expense of increased metabolism, and if this increase were completely converted into mechanical effect, the heat production in the organism might remain the same as in the resting state. If, however, the result of mechanical effort should be a stimulation of metabolism to the extent of not only enabling the body to do work but also causing

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