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Article
July 2, 1927

THE NASAL APPLICATION OF SOLUTION OF PITUITARY FOR OBSTETRIC PURPOSESPRELIMINARY COMMUNICATION

JAMA. 1927;89(1):24-25. doi:10.1001/jama.1927.02690010024009

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Abstract

The recent clinical study of Scott on the present state of the induction of labor revealed the fact that, up to this time, no method has been devised which is altogether free from danger to either mother or child, and more particularly that Watson's technic is sometimes followed by death of the infant, owing, for the most part, to the tetanic contraction of the uterus which sometimes follows the use of solution of pituitary. Watson's method is based on the sensitization of the uterine muscle by the administration of castor oil and quinine, followed by the subcutaneous injection of 0.5 cc. of solution of pituitary at half hour intervals, until labor sets in or until six doses have been given. Those who have had experience with the method agree that undue sensibility to the action of solution of pituitary may lead to disastrous effects on the child; and as this

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